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Experimental Therapeutics |
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| The Experimental Therapeutics Core at the Animal Cancer Center includes drug discovery, effectiveness of treatment, and pharmacology. Faculty members in this group include medical oncologists, cancer biologists and a pharmacologist. |
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| The pharmacology service includes consultation on pharmakinetic study design, analytical assays for drugs in tissue and fluids, and PK modeling and mathematical analysis of data. Equipment includes: |
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Equimpnet includes: |
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HPLC analysis with fluorescence detection and LC coupled to tandem mass spectrometry |
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Two ABI3200 linear trap triple quadropole instrument |
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• Agilent 1200 Series LC system with HTC-PAL autosampler |
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• Shimadzu LC system with HTC-PAL autosampler |
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Rotary evaporator for sample prep |
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Solid phase extraction manifold |
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Current production capacity is approximately 400 samples per day, 1,600 samples per week and 20,000 samples annually. Turn around is generally 1-4 weeks, but possible within 24 hours. Batches of over 40 samples with validated assays are analyzed within 4 weeks. |
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