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Animal Study Subjects |
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| Study subjects at the Animal Cancer Center (ACC) are client owned companion animals (dogs and cats) with spontaneously occurring cancers. These animals, especially dogs, are excellent research models because: |
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Cancers resemble humans in size, cell kinetics, and biology |
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“Real-world” environment (not artificial laboratory) |
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Highly compliant patients (motivated owners) |
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Human-like treatment protocols: adjunctive to surgery, chemotherapy and radiation therapy |
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Novel drug vectors are feasible |
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Patients are not immuno-compromised, inbred-rodents with xenobiotic implanted tumors |
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Cancer Treatment research community and investment decision makers put high value on companion animal data |
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Genetically diverse like humans |
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Genetically diverse like humans |
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Similar oncogenes and tumor suppressor pathways to humans |
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Comparative histologies in melanoma, NHL, leukemia, OSA, soft tissue sarcoma, prostate, mammary, lung, head and neck and bladder carcinoma |
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Excellent model to study new treatment methods (inhalation) and to develop translatable novel therapeutics |
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More time efficient, less cost, better model than rodents |
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